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Formulation Considerations for Autologous T Cell Drug Products
Genetically modified autologous T cells have become an established immunotherapy in the fight against cancer. The manufacture of chimeric antigen receptor (CAR) and αβ-T cell receptor (TCR) transduced T cells poses unique challenges, including the formulation, cryopreservation and fill–finish steps,...
Autores principales: | van der Walle, Christopher F., Godbert, Sonya, Saito, Gabriele, Azhari, Zein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400304/ https://www.ncbi.nlm.nih.gov/pubmed/34452278 http://dx.doi.org/10.3390/pharmaceutics13081317 |
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