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Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population

This review describes acetaminophen pharmacokinetics (PK) throughout pregnancy, as analyzed by three methods (non-compartmental analyses (NCA), population PK, and physiologically based PK (PBPK) modelling). Eighteen studies using NCA were reported in the scientific literature. These studies reported...

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Detalles Bibliográficos
Autores principales: Brookhuis, Sofie A. M., Allegaert, Karel, Hanff, Lidwien M., Lub-de Hooge, Marjolijn N., Dallmann, André, Mian, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400310/
https://www.ncbi.nlm.nih.gov/pubmed/34452263
http://dx.doi.org/10.3390/pharmaceutics13081302