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Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population
This review describes acetaminophen pharmacokinetics (PK) throughout pregnancy, as analyzed by three methods (non-compartmental analyses (NCA), population PK, and physiologically based PK (PBPK) modelling). Eighteen studies using NCA were reported in the scientific literature. These studies reported...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400310/ https://www.ncbi.nlm.nih.gov/pubmed/34452263 http://dx.doi.org/10.3390/pharmaceutics13081302 |