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Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population

This review describes acetaminophen pharmacokinetics (PK) throughout pregnancy, as analyzed by three methods (non-compartmental analyses (NCA), population PK, and physiologically based PK (PBPK) modelling). Eighteen studies using NCA were reported in the scientific literature. These studies reported...

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Detalles Bibliográficos
Autores principales:	Brookhuis, Sofie A. M., Allegaert, Karel, Hanff, Lidwien M., Lub-de Hooge, Marjolijn N., Dallmann, André, Mian, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400310/ https://www.ncbi.nlm.nih.gov/pubmed/34452263 http://dx.doi.org/10.3390/pharmaceutics13081302

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