Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics

Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotracer [(18)F]fluoromethyl-[1,2-(2)H(4)]-choline ([(18)...

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Detalles Bibliográficos
Autores principales: Li, Yunqing, Inglese, Marianna, Dubash, Suraiya, Barnes, Chris, Brickute, Diana, Braga, Marta Costa, Wang, Ning, Beckley, Alice, Heinzmann, Kathrin, Allott, Louis, Lu, Haonan, Chen, Cen, Fu, Ruisi, Carroll, Laurence, Aboagye, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400349/
https://www.ncbi.nlm.nih.gov/pubmed/34452207
http://dx.doi.org/10.3390/pharmaceutics13081246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400349/
https://www.ncbi.nlm.nih.gov/pubmed/34452207
http://dx.doi.org/10.3390/pharmaceutics13081246

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