New Insights into Beta-Lactam Resistance of Streptococcus pneumoniae: Serine Protease HtrA Degrades Altered Penicillin-Binding Protein 2x

Reduced amounts of the essential penicillin-binding protein 2x (PBP2x) were detected in two cefotaxime-resistant Streptococcus pneumoniae laboratory mutants C405 and C606. These mutants contain two or four mutations in the penicillin-binding domain of PBP2x, respectively. The transcription of the pb...

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Detalles Bibliográficos
Autores principales: Peters, Katharina, Schweizer, Inga, Hakenbeck, Regine, Denapaite, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400419/
https://www.ncbi.nlm.nih.gov/pubmed/34442764
http://dx.doi.org/10.3390/microorganisms9081685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400419/
https://www.ncbi.nlm.nih.gov/pubmed/34442764
http://dx.doi.org/10.3390/microorganisms9081685

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