Synthesis, Antibacterial and Pharmacokinetic Evaluation of Novel Derivatives of Harmine N(9)-Cinnamic Acid

A series of 16 new derivatives of harmine N(9)-Cinnamic acid were synthesized and fully characterized using NMR and MS. The in vitro antibacterial evaluation revealed that most of the synthesized harmine derivatives displayed better antibacterial activities against Gram-positive strains (S. aureus,...

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Detalles Bibliográficos
Autores principales: Liang, Yan, He, Dian, Zhou, Deshun, Li, Junshuai, Tang, Lei, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400480/
https://www.ncbi.nlm.nih.gov/pubmed/34443429
http://dx.doi.org/10.3390/molecules26164842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400480/
https://www.ncbi.nlm.nih.gov/pubmed/34443429
http://dx.doi.org/10.3390/molecules26164842

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