TPMT*3C as a Predictor of 6-Mercaptopurine-Induced Myelotoxicity in Thai Children with Acute Lymphoblastic Leukemia

The response to 6-mercaptopurine (6-MP) can be altered by genetic polymorphisms in genes encoding drug-metabolizing enzymes and drug transporters. The purpose of this study was to investigate the association between genetic polymorphisms of drug-metabolizing enzymes (TPMT 719A > G (*3C), ITPA 94C...

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Detalles Bibliográficos
Autores principales: Jantararoungtong, Thawinee, Wiwattanakul, Supaporn, Tiyasirichokchai, Rawiporn, Prommas, Santirhat, Sukprasong, Rattanaporn, Koomdee, Napatrupron, Jinda, Pimonpan, Rachanakul, Jiratha, Nuntharadthanaphong, Nutthan, Pakakasama, Samart, Anurathapan, Usanarat, Hongeng, Suradej, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400562/
https://www.ncbi.nlm.nih.gov/pubmed/34442427
http://dx.doi.org/10.3390/jpm11080783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400562/
https://www.ncbi.nlm.nih.gov/pubmed/34442427
http://dx.doi.org/10.3390/jpm11080783

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