Urinary 2-Hydroxyglutarate Enantiomers Are Markedly Elevated in a Murine Model of Type 2 Diabetic Kidney Disease

Metabolic reprogramming is a hallmark of diabetic kidney disease (DKD); nutrient overload leads to increased production of metabolic byproducts that may become toxic at high levels. One metabolic byproduct may be 2-hydroxyglutarate (2-HG), a metabolite with many regulatory functions that exists in b...

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Detalles Bibliográficos
Autores principales: Baek, Judy, Pennathur, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400583/
https://www.ncbi.nlm.nih.gov/pubmed/34436410
http://dx.doi.org/10.3390/metabo11080469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400583/
https://www.ncbi.nlm.nih.gov/pubmed/34436410
http://dx.doi.org/10.3390/metabo11080469

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