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The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG75 as Examples

Salivarian trypanosomes comprise a group of extracellular anthroponotic and zoonotic parasites. The only sustainable method for global control of these infection is through vaccination of livestock animals. Despite multiple reports describing promising laboratory results, no single field-applicable...

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Detalles Bibliográficos
Autores principales: Magez, Stefan, Li, Zeng, Nguyen, Hang Thi Thu, Pinto Torres, Joar Esteban, Van Wielendaele, Pieter, Radwanska, Magdalena, Began, Jakub, Zoll, Sebastian, Sterckx, Yann G.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400590/
https://www.ncbi.nlm.nih.gov/pubmed/34451514
http://dx.doi.org/10.3390/pathogens10081050