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Structure and Glass Transition Temperature of Amorphous Dispersions of Model Pharmaceuticals with Nucleobases from Molecular Dynamics

Glass transition temperature (T(g)) is an important material property, which predetermines the kinetic stability of amorphous solids. In the context of active pharmaceutical ingredients (API), there is motivation to maximize their T(g) by forming amorphous mixtures with other chemicals, labeled exci...

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Detalles Bibliográficos
Autores principales: Červinka, Ctirad, Fulem, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400648/
https://www.ncbi.nlm.nih.gov/pubmed/34452214
http://dx.doi.org/10.3390/pharmaceutics13081253