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A Novel Cardenolide Glycoside Isolated from Xysmalobium undulatum Reduces Levels of the Alzheimer’s Disease-Associated β-Amyloid Peptides Aβ42 In Vitro

Elevated levels of the amylo β-proteins (Aβ), particularly Aβ42, are associated with a high risk of Alzheimer’s disease (AD). The Aβ proteins are produced from cellular processing of the amyloid precursor proteins (APPs). To identify natural products that block the formation of Aβ-proteins from APPs...

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Detalles Bibliográficos
Autores principales: Thakur, Anuradha, Moyo, Phanankosi, van der Westhuizen, Carl Johan, Yang, Hyun Ok, Maharaj, Vinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400651/
https://www.ncbi.nlm.nih.gov/pubmed/34451840
http://dx.doi.org/10.3390/ph14080743