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Development, Characterization, and In Vivo Evaluation of a Novel Aptamer (Anti-MUC1/Y) for Breast Cancer Therapy

MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by...

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Detalles Bibliográficos
Autores principales: Khan, Huma, Makwana, Vaidehi, dos Santos, Sofia Nascimento, Bonacossa de Almeida, Carlos Eduardo, Santos-Oliveira, Ralph, Missailidis, Sotiris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400696/
https://www.ncbi.nlm.nih.gov/pubmed/34452200
http://dx.doi.org/10.3390/pharmaceutics13081239