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Development, Characterization, and In Vivo Evaluation of a Novel Aptamer (Anti-MUC1/Y) for Breast Cancer Therapy
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by...
Autores principales: | Khan, Huma, Makwana, Vaidehi, dos Santos, Sofia Nascimento, Bonacossa de Almeida, Carlos Eduardo, Santos-Oliveira, Ralph, Missailidis, Sotiris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400696/ https://www.ncbi.nlm.nih.gov/pubmed/34452200 http://dx.doi.org/10.3390/pharmaceutics13081239 |
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