Combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR to Monitor In Vitro Vitetrifolin D Phase I and II Metabolism

By combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR, the in vitro metabolism of vitetrifolin D, a pharmacologically active key molecule from Vitex agnus-castus in liver cell fractions, was investigated. Twenty-seven phase I and phase II metabolites were tentatively identified from the culture broth by HP...

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Detalles Bibliográficos
Autores principales: Sturm, Sonja, Högner, Christina, Seger, Christoph, Stuppner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400717/
https://www.ncbi.nlm.nih.gov/pubmed/34436470
http://dx.doi.org/10.3390/metabo11080529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400717/
https://www.ncbi.nlm.nih.gov/pubmed/34436470
http://dx.doi.org/10.3390/metabo11080529

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