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Prevalence of Mutations in the pfcoronin Gene and Association with Ex Vivo Susceptibility to Common Quinoline Drugs against Plasmodium falciparum

Background: Artemisinin-based combination therapy (ACT) was recommended to treat uncomplicated falciparum malaria. Unlike the situation in Asia where resistance to ACT has been reported, artemisinin resistance has not yet emerged in Africa. However, some rare failures with ACT or patients continuing...

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Detalles Bibliográficos
Autores principales: Delandre, Océane, Gendrot, Mathieu, Fonta, Isabelle, Mosnier, Joel, Benoit, Nicolas, Amalvict, Rémy, Gomez, Nicolas, Madamet, Marylin, Pradines, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400718/
https://www.ncbi.nlm.nih.gov/pubmed/34452235
http://dx.doi.org/10.3390/pharmaceutics13081273