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Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21

Blockers of angiotensin II type 1 receptor (AT1R) exert antidepressant-like effects by indirectly facilitating the activation of the angiotensin II type 2 receptor (AT2R), which leads to increased surface expression and transactivation of tropomyosin-related kinase B receptors (TRKB). Compound 21 (C...

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Detalles Bibliográficos
Autores principales: Laukkanen, Liina, Diniz, Cassiano R. A. F., Foulquier, Sebastien, Prickaerts, Jos, Castrén, Eero, Casarotto, Plinio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400827/
https://www.ncbi.nlm.nih.gov/pubmed/34451870
http://dx.doi.org/10.3390/ph14080773