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Thermostable and Long-Circulating Albumin-Conjugated Arthrobacter globiformis Urate Oxidase

Urate oxidase derived from Aspergillus flavus has been investigated as a treatment for tumor lysis syndrome, hyperuricemia, and gout. However, its long-term use is limited owing to potential immunogenicity, low thermostability, and short circulation time in vivo. Recently, urate oxidase isolated fro...

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Detalles Bibliográficos
Autores principales: Yang, Byungseop, Kwon, Inchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400835/
https://www.ncbi.nlm.nih.gov/pubmed/34452259
http://dx.doi.org/10.3390/pharmaceutics13081298