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Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology

Alzheimer’s disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ) peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary tangles. Extensive research has focused on understanding the assembly mechanisms and neurotoxic effects of Aβ duri...

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Detalles Bibliográficos
Autores principales: Rahman, M. Mahafuzur, Lendel, Christofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400902/
https://www.ncbi.nlm.nih.gov/pubmed/34454574
http://dx.doi.org/10.1186/s13024-021-00465-0