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Association of HLA-B*51:01, HLA-B*55:01, CYP2C9*3, and Phenytoin-Induced Cutaneous Adverse Drug Reactions in the South Indian Tamil Population

Phenytoin (PHT) is one of the most commonly reported aromatic anti-epileptic drugs (AEDs) to cause cutaneous adverse reactions (CADRs), particularly severe cutaneous adverse reactions (SCARs). Although human leukocyte antigen (HLA)-B*15:02 is associated with PHT-induced Steven Johnson syndrome/toxic...

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Detalles Bibliográficos
Autores principales: John, Shobana, Balakrishnan, Karuppiah, Sukasem, Chonlaphat, Anand, Tharmarajan Chinnathambi Vijay, Canyuk, Bhutorn, Pattharachayakul, Sutthiporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400937/
https://www.ncbi.nlm.nih.gov/pubmed/34442381
http://dx.doi.org/10.3390/jpm11080737