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The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity

Investigation of drug-induced liver injuries requires appropriate in vivo and in vitro toxicological model systems. In our study, an attempt was made to compare the hepatocarcinoma HepG2 and the stem cell-derived HepaRG cell lines both in two- and three-dimensional culture conditions to find the mos...

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Detalles Bibliográficos
Autores principales: Lőrincz, Tamás, Deák, Veronika, Makk-Merczel, Kinga, Varga, Dóra, Hajdinák, Péter, Szarka, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400973/
https://www.ncbi.nlm.nih.gov/pubmed/34440600
http://dx.doi.org/10.3390/life11080856