Filamentous Fungi Producing l-Asparaginase with Low Glutaminase Activity Isolated from Brazilian Savanna Soil

l-asparaginase is an enzyme used as treatment for acute lymphoblastic leukemia (ALL) due to its ability to hydrolyze l-asparagine, an essential amino acid synthesized by normal cells unlike neoplastic cells. The adverse effects of l-asparaginase formulations are associated with its glutaminase activ...

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Detalles Bibliográficos
Autores principales: Freitas, Marcela, Souza, Paula, Cardoso, Samuel, Cruvinel, Kellen, Abrunhosa, Letícia Santos, Ferreira Filho, Edivaldo X., Inácio, João, Pinho, Danilo Batista, Pessoa, Adalberto, O. Magalhães, Pérola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401000/
https://www.ncbi.nlm.nih.gov/pubmed/34452229
http://dx.doi.org/10.3390/pharmaceutics13081268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401000/
https://www.ncbi.nlm.nih.gov/pubmed/34452229
http://dx.doi.org/10.3390/pharmaceutics13081268

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