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Filamentous Fungi Producing l-Asparaginase with Low Glutaminase Activity Isolated from Brazilian Savanna Soil

l-asparaginase is an enzyme used as treatment for acute lymphoblastic leukemia (ALL) due to its ability to hydrolyze l-asparagine, an essential amino acid synthesized by normal cells unlike neoplastic cells. The adverse effects of l-asparaginase formulations are associated with its glutaminase activ...

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Detalles Bibliográficos
Autores principales:	Freitas, Marcela, Souza, Paula, Cardoso, Samuel, Cruvinel, Kellen, Abrunhosa, Letícia Santos, Ferreira Filho, Edivaldo X., Inácio, João, Pinho, Danilo Batista, Pessoa, Adalberto, O. Magalhães, Pérola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401000/ https://www.ncbi.nlm.nih.gov/pubmed/34452229 http://dx.doi.org/10.3390/pharmaceutics13081268

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