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Largazole Inhibits Ocular Angiogenesis by Modulating the Expression of VEGFR2 and p21

Ocular angiogenic diseases, characterized by abnormal blood vessel formation in the eye, are the leading cause of blindness. Although Anti-VEGF therapy is the first-line treatment in the market, a substantial number of patients are refractory to it or may develop resistance over time. As uncontrolle...

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Detalles Bibliográficos
Autores principales: Qiu, Beiying, Tan, Alison, Tan, Yu Zhi, Chen, Qi-Yin, Luesch, Hendrik, Wang, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401058/
https://www.ncbi.nlm.nih.gov/pubmed/34436310
http://dx.doi.org/10.3390/md19080471