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An Efficient Synthesis of 2-CF(3)-3-Benzylindoles
The reaction of α-CF(3)-β-(2-nitroaryl) enamines with benzaldehydes afforded effectively α,β-diaryl-CF(3)-enones having nitro group. Subsequent reduction of nitro group by NH(4)HCO(2)-Pd/C system initiated intramolecular cyclization to give 2-CF(3)-3-benzylindoles. Target products can be prepared in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401147/ https://www.ncbi.nlm.nih.gov/pubmed/34443672 http://dx.doi.org/10.3390/molecules26165084 |