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An Efficient Synthesis of 2-CF(3)-3-Benzylindoles

The reaction of α-CF(3)-β-(2-nitroaryl) enamines with benzaldehydes afforded effectively α,β-diaryl-CF(3)-enones having nitro group. Subsequent reduction of nitro group by NH(4)HCO(2)-Pd/C system initiated intramolecular cyclization to give 2-CF(3)-3-benzylindoles. Target products can be prepared in...

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Detalles Bibliográficos
Autores principales:	Muzalevskiy, Vasiliy M., Sizova, Zoia A., Nenajdenko, Valentine G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401147/ https://www.ncbi.nlm.nih.gov/pubmed/34443672 http://dx.doi.org/10.3390/molecules26165084

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