Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a severe progressive muscle disease that is frequently associated with secondary osteoporosis. Previous studies have shown that TGFbeta inactivating antibody improves the muscle phenotype in mdx mice, a model of DMD. In the present study, we assessed the skeletal...

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Detalles Bibliográficos
Autores principales: Marulanda, Juliana, Boraschi-Diaz, Iris, Beauparlant, Pierre, Crine, Philippe, Rauch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401157/
https://www.ncbi.nlm.nih.gov/pubmed/34440535
http://dx.doi.org/10.3390/life11080791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401157/
https://www.ncbi.nlm.nih.gov/pubmed/34440535
http://dx.doi.org/10.3390/life11080791

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