Titania Nanosheet Generates Peroxynitrite-Dependent S-Nitrosylation and Enhances p53 Function in Lung Cancer Cells

Metal nanomaterials can enhance the efficacy of current cancer therapies. Here, we show that Ti(0)(.8)O(2) nanosheets cause cytotoxicity in several lung cancer cells but not in normal cells. The nanosheet-treated cells showed certain apoptosis characteristics. Protein analysis further indicated the...

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Detalles Bibliográficos
Autores principales: Soonnarong, Rapeepun, Tungsukruthai, Sucharat, Nutho, Bodee, Rungrotmongkol, Thanyada, Vinayanuwattikun, Chanida, Maluangnont, Tosapol, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401232/
https://www.ncbi.nlm.nih.gov/pubmed/34452194
http://dx.doi.org/10.3390/pharmaceutics13081233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401232/
https://www.ncbi.nlm.nih.gov/pubmed/34452194
http://dx.doi.org/10.3390/pharmaceutics13081233

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