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In Silico Identification of Cholesterol Binding Motifs in the Chemokine Receptor CCR3

CC motif chemokine receptor 3 (CCR3) is a Class A G protein-coupled receptor (GPCR) mainly responsible for the cellular trafficking of eosinophils. As such, it plays key roles in inflammatory conditions, such as asthma and arthritis, and the metastasis of many deadly forms of cancer. However, little...

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Detalles Bibliográficos
Autores principales: van Aalst, Evan, Koneri, Jotham, Wylie, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401243/
https://www.ncbi.nlm.nih.gov/pubmed/34436333
http://dx.doi.org/10.3390/membranes11080570