Cargando…
In Silico Identification of Cholesterol Binding Motifs in the Chemokine Receptor CCR3
CC motif chemokine receptor 3 (CCR3) is a Class A G protein-coupled receptor (GPCR) mainly responsible for the cellular trafficking of eosinophils. As such, it plays key roles in inflammatory conditions, such as asthma and arthritis, and the metastasis of many deadly forms of cancer. However, little...
Autores principales: | van Aalst, Evan, Koneri, Jotham, Wylie, Benjamin J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401243/ https://www.ncbi.nlm.nih.gov/pubmed/34436333 http://dx.doi.org/10.3390/membranes11080570 |
Ejemplares similares
-
Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling
por: van Aalst, Evan, et al.
Publicado: (2021) -
Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10
por: Lim, Herman D., et al.
Publicado: (2021) -
Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3
por: Shao, Zhehua, et al.
Publicado: (2022) -
Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5
por: Zhang, Hui, et al.
Publicado: (2021) -
Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1
por: Shao, Zhehua, et al.
Publicado: (2021)