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Quantitative Analysis of the Membrane Affinity of Local Anesthetics Using a Model Cell Membrane

Local anesthesia is a drug that penetrates the nerve cell membrane and binds to the voltage gate sodium channel, inhibiting the membrane potential and neurotransmission. It is mainly used in clinical uses to address the pain of surgical procedures in the local area. Local anesthetics (LAs), however,...

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Detalles Bibliográficos
Autores principales: Choi, Wanjae, Ryu, Hyunil, Fuwad, Ahmed, Goh, Seulmini, Zhou, Chaoge, Shim, Jiwook, Takagi, Masahiro, Kwon, Soonjo, Kim, Sun Min, Jeon, Tae-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401255/
https://www.ncbi.nlm.nih.gov/pubmed/34436342
http://dx.doi.org/10.3390/membranes11080579