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Quantitative Analysis of the Membrane Affinity of Local Anesthetics Using a Model Cell Membrane
Local anesthesia is a drug that penetrates the nerve cell membrane and binds to the voltage gate sodium channel, inhibiting the membrane potential and neurotransmission. It is mainly used in clinical uses to address the pain of surgical procedures in the local area. Local anesthetics (LAs), however,...
Autores principales: | Choi, Wanjae, Ryu, Hyunil, Fuwad, Ahmed, Goh, Seulmini, Zhou, Chaoge, Shim, Jiwook, Takagi, Masahiro, Kwon, Soonjo, Kim, Sun Min, Jeon, Tae-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401255/ https://www.ncbi.nlm.nih.gov/pubmed/34436342 http://dx.doi.org/10.3390/membranes11080579 |
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