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A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs

Coenzyme A (CoA) is an essential cofactor for dozens of reactions in intermediary metabolism. Dysregulation of CoA synthesis or acyl CoA metabolism can result in metabolic or neurodegenerative disease. Although several methods use liquid chromatography coupled with mass spectrometry/mass spectrometr...

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Detalles Bibliográficos
Autores principales: Jones, Anthony E., Arias, Nataly J., Acevedo, Aracely, Reddy, Srinivasa T., Divakaruni, Ajit S., Meriwether, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401288/
https://www.ncbi.nlm.nih.gov/pubmed/34436409
http://dx.doi.org/10.3390/metabo11080468