Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1

Background: Eukaryotic topoisomerase 1 is a potential target of anti-parasitic and anti-cancer drugs. Parasites require topoisomerase 1 activity for survival and, consequently, compounds that inhibit topoisomerase 1 activity may be of interest. All effective topoisomerase 1 drugs with anti-cancer ac...

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Detalles Bibliográficos
Autores principales: Petersen, Kamilla Vandsø, Selas, Asier, Hymøller, Kirstine Mejlstrup, Mizielinski, Karol, Thorsager, Maria, Stougaard, Magnus, Alonso, Concepcion, Palacios, Francisco, Pérez-Pertejo, Yolanda, Reguera, Rosa M., Balaña-Fouce, Rafael, Knudsen, Birgitta R., Tesauro, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401307/
https://www.ncbi.nlm.nih.gov/pubmed/34452216
http://dx.doi.org/10.3390/pharmaceutics13081255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401307/
https://www.ncbi.nlm.nih.gov/pubmed/34452216
http://dx.doi.org/10.3390/pharmaceutics13081255

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