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Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts

OBJECTIVES: T cells have an essential role in the antiviral defence. Public T‐cell receptor (TCR) clonotypes are expanded in a substantial proportion of COVID‐19 patients. We set out to exploit their potential use as read‐out for COVID‐19 T‐cell immune responses. METHODS: We searched for COVID‐19‐as...

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Detalles Bibliográficos
Autores principales: Simnica, Donjete, Schultheiß, Christoph, Mohme, Malte, Paschold, Lisa, Willscher, Edith, Fitzek, Antonia, Püschel, Klaus, Matschke, Jakob, Ciesek, Sandra, Sedding, Daniel G, Zhao, Yu, Gagliani, Nicola, Maringer, Yacine, Walz, Juliane S, Heide, Janna, Schulze‐zur‐Wiesch, Julian, Binder, Mascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401425/
https://www.ncbi.nlm.nih.gov/pubmed/34484739
http://dx.doi.org/10.1002/cti2.1340