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Antioxidant Activity of Deferasirox and Its Metal Complexes in Model Systems of Oxidative Damage: Comparison with Deferiprone

Deferasirox is an orally active, lipophilic iron chelating drug used on thousands of patients worldwide for the treatment of transfusional iron overload. The essential transition metals iron and copper are the primary catalysts of reactive oxygen species and oxidative damage in biological systems. T...

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Detalles Bibliográficos
Autores principales: Timoshnikov, Viktor A., Kichigina, Lilia A., Selyutina, Olga Yu., Polyakov, Nikolay E., Kontoghiorghes, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401497/
https://www.ncbi.nlm.nih.gov/pubmed/34443652
http://dx.doi.org/10.3390/molecules26165064