Re-Evaluations of Zr-DFO Complex Coordination Chemistry for the Estimation of Radiochemical Yields and Chelator-to-Antibody Ratios of (89)Zr Immune-PET Tracers

(1) Background: Deferoxamine B (DFO) is the most widely used chelator for labeling of zirconium-89 ((89)Zr) to monoclonal antibody (mAb). Despite the remarkable developments of the clinical (89)Zr-immuno-PET, chemical species and stability constants of the Zr-DFO complexes remain controversial. The...

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Detalles Bibliográficos
Autores principales: Imura, Ryota, Ida, Hiroyuki, Sasaki, Ichiro, Ishioka, Noriko S., Watanabe, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401698/
https://www.ncbi.nlm.nih.gov/pubmed/34443566
http://dx.doi.org/10.3390/molecules26164977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401698/
https://www.ncbi.nlm.nih.gov/pubmed/34443566
http://dx.doi.org/10.3390/molecules26164977

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