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Platelet APP Processing: Is It a Tool to Explore the Pathophysiology of Alzheimer’s Disease? A Systematic Review

The processing of the amyloid precursor protein (APP) is a critical event in the formation of amyloid plaques. Platelets contain most of the enzymatic machinery required for APP processing and correlates of intracerebral abnormalities have been demonstrated in platelets of patients with AD. The goal...

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Detalles Bibliográficos
Autores principales: Carbone, Manuel Glauco, Pagni, Giovanni, Tagliarini, Claudia, Marazziti, Donatella, Pomara, Nunzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401829/
https://www.ncbi.nlm.nih.gov/pubmed/34440494
http://dx.doi.org/10.3390/life11080750