Assessing the Inhibitory Potential of Kinase Inhibitors In Vitro: Major Pitfalls and Suggestions for Improving Comparability of Data Using CK1 Inhibitors as an Example

Phosphorylation events catalyzed by protein kinases represent one of the most prevalent as well as important regulatory posttranslational modifications, and dysregulation of protein kinases is associated with the pathogenesis of different diseases. Therefore, interest in developing potent small mole...

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Detalles Bibliográficos
Autores principales: Roth, Aileen, Gihring, Adrian, Göser, Florian, Peifer, Christian, Knippschild, Uwe, Bischof, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401859/
https://www.ncbi.nlm.nih.gov/pubmed/34443486
http://dx.doi.org/10.3390/molecules26164898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401859/
https://www.ncbi.nlm.nih.gov/pubmed/34443486
http://dx.doi.org/10.3390/molecules26164898

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