Palonosetron/Methyllycaconitine Deactivate Hippocampal Microglia 1, Inflammasome Assembly and Pyroptosis to Enhance Cognition in a Novel Model of Neuroinflammation

Since westernized diet-induced insulin resistance is a risk factor in Alzheimer’s disease (AD) development, and lipopolysaccharide (LPS) coexists with amyloid β (Aβ)1-42 in these patients, our AD novel model was developed to resemble sporadic AD by injecting LPS into high fat/fructose diet (HFFD)-fe...

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Detalles Bibliográficos
Autores principales: Mohamed, Reem A., Abdallah, Dalaal M., El-brairy, Amany I., Ahmed, Kawkab A., El-Abhar, Hanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401912/
https://www.ncbi.nlm.nih.gov/pubmed/34443654
http://dx.doi.org/10.3390/molecules26165068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401912/
https://www.ncbi.nlm.nih.gov/pubmed/34443654
http://dx.doi.org/10.3390/molecules26165068

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