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Metformin Decreases 2-HG Production through the MYC-PHGDH Pathway in Suppressing Breast Cancer Cell Proliferation

The biguanide drug metformin has been widely used for the treatment of type 2 diabetes, and there is evidence supporting the anticancer effect of metformin despite some controversy. Here, we report the growth inhibitory activity of metformin in the breast cancer (MCF-7) cells, both in vitro and in v...

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Detalles Bibliográficos
Autores principales:	Oh, Sehyun, Cho, Youngup, Chang, Minsun, Park, Sunghyouk, Kwon, Hyuknam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402004/ https://www.ncbi.nlm.nih.gov/pubmed/34436421 http://dx.doi.org/10.3390/metabo11080480

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