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An Iron Shield to Protect Epigallocatehin-3-Gallate from Degradation: Multifunctional Self-Assembled Iron Oxide Nanocarrier Enhances Protein Kinase CK2 Intracellular Targeting and Inhibition

Protein kinase CK2 is largely involved in cell proliferation and apoptosis and is generally recognized as an Achilles’ heel of cancer, being overexpressed in several malignancies. The beneficial effects of (−)-epigallocatechin-3-gallate (EGCG) in the prevention and treatment of several diseases, inc...

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Detalles Bibliográficos
Autores principales: Fasolato, Luca, Magro, Massimiliano, Cozza, Giorgio, Sbarra, Ferruccio, Molinari, Simone, Novelli, Enrico, Vianello, Fabio, Venerando, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402011/
https://www.ncbi.nlm.nih.gov/pubmed/34452227
http://dx.doi.org/10.3390/pharmaceutics13081266