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Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form of Pseudomonas aeruginosa Exotoxin A

The low permeability of nanoparticles (NPs) across the intestinal epithelium remains a major challenge for their application of delivering macromolecular therapeutic agents via the oral route. Previous studies have demonstrated the epithelial transcytosis capacity of a non-toxic version of Pseudomon...

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Detalles Bibliográficos
Autores principales: Li, Ruiying, Laurent, Floriane, Taverner, Alistair, Mackay, Julia, De Bank, Paul A., Mrsny, Randall J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402016/
https://www.ncbi.nlm.nih.gov/pubmed/34452131
http://dx.doi.org/10.3390/pharmaceutics13081171