Regulation of Antigenic Variation by Trypanosoma brucei Telomere Proteins Depends on Their Unique DNA Binding Activities

Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, Variant Surface Glycoprotein (VSG), to evade the host immune response. Such antigenic variation is a key pathogenesis mechanism that enables T. brucei to establish long-term infections. VSG is e...

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Detalles Bibliográficos
Autores principales: Li, Bibo, Zhao, Yanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402208/
https://www.ncbi.nlm.nih.gov/pubmed/34451431
http://dx.doi.org/10.3390/pathogens10080967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402208/
https://www.ncbi.nlm.nih.gov/pubmed/34451431
http://dx.doi.org/10.3390/pathogens10080967

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