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The Dragon’s Paralysing Spell: Evidence of Sodium and Calcium Ion Channel Binding Neurotoxins in Helodermatid and Varanid Lizard Venoms

Bites from helodermatid lizards can cause pain, paresthesia, paralysis, and tachycardia, as well as other symptoms consistent with neurotoxicity. Furthermore, in vitro studies have shown that Heloderma horridum venom inhibits ion flux and blocks the electrical stimulation of skeletal muscles. Helode...

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Detalles Bibliográficos
Autores principales: Dobson, James S., Harris, Richard J., Zdenek, Christina N., Huynh, Tam, Hodgson, Wayne C., Bosmans, Frank, Fourmy, Rudy, Violette, Aude, Fry, Bryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402328/
https://www.ncbi.nlm.nih.gov/pubmed/34437420
http://dx.doi.org/10.3390/toxins13080549