Human Transbodies to Reverse Transcriptase Connection Subdomain of HIV-1 Gag-Pol Polyprotein Reduce Infectiousness of the Virus Progeny

HIV-1 progeny are released from infected cells as immature particles that are unable to infect new cells. Gag-Pol polyprotein dimerization via the reverse transcriptase connection domain (RTCDs) is pivotal for proper activation of the virus protease (PR protein) in an early event of the progeny viru...

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Detalles Bibliográficos
Autores principales: Seesuay, Watee, Phanthong, Siratcha, Densumite, Jaslan, Mahasongkram, Kodchakorn, Sookrung, Nitat, Chaicumpa, Wanpen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402387/
https://www.ncbi.nlm.nih.gov/pubmed/34452018
http://dx.doi.org/10.3390/vaccines9080893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402387/
https://www.ncbi.nlm.nih.gov/pubmed/34452018
http://dx.doi.org/10.3390/vaccines9080893

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