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A Single-Cycle Influenza A Virus-Based SARS-CoV-2 Vaccine Elicits Potent Immune Responses in a Mouse Model

The use of virus-vectored platforms has increasingly gained attention in vaccine development as a means for delivering antigenic genes of interest into target hosts. Here, we describe a single-cycle influenza virus-based SARS-CoV-2 vaccine designated as scPR8-RBD-M2. The vaccine utilizes the chimeri...

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Detalles Bibliográficos
Autores principales: Koonpaew, Surapong, Kaewborisuth, Challika, Srisutthisamphan, Kanjana, Wanitchang, Asawin, Thaweerattanasinp, Theeradej, Saenboonrueng, Janya, Poonsuk, Sukontip, Jengarn, Juggragarn, Viriyakitkosol, Ratchanont, Kramyu, Jarin, Jongkaewwattana, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402467/
https://www.ncbi.nlm.nih.gov/pubmed/34451975
http://dx.doi.org/10.3390/vaccines9080850