DNA Vaccine Administered by Cationic Lipoplexes or by In Vivo Electroporation Induces Comparable Antibody Responses against SARS-CoV-2 in Mice

In view of addressing the global necessity of an effective vaccine in the SARS-CoV-2 pandemic, a plasmid DNA vaccine, expressing for the spike (S) protein and formulated in lipoplexes, was manufactured and tested for in vitro transfection and in vivo immunogenicity. Blank cationic liposomes of 130.9...

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Detalles Bibliográficos
Autores principales: Peletta, Allegra, Prompetchara, Eakachai, Tharakhet, Kittipan, Kaewpang, Papatsara, Buranapraditkun, Supranee, Techawiwattanaboon, Teerasit, Jbilou, Tayeb, Krangvichian, Pratomporn, Sirivichayakul, Sunee, Manopwisedjaroen, Suwimon, Thitithanyanont, Arunee, Patarakul, Kanitha, Ruxrungtham, Kiat, Ketloy, Chutitorn, Borchard, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402479/
https://www.ncbi.nlm.nih.gov/pubmed/34451998
http://dx.doi.org/10.3390/vaccines9080874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402479/
https://www.ncbi.nlm.nih.gov/pubmed/34451998
http://dx.doi.org/10.3390/vaccines9080874

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