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DNA Vaccine Administered by Cationic Lipoplexes or by In Vivo Electroporation Induces Comparable Antibody Responses against SARS-CoV-2 in Mice
In view of addressing the global necessity of an effective vaccine in the SARS-CoV-2 pandemic, a plasmid DNA vaccine, expressing for the spike (S) protein and formulated in lipoplexes, was manufactured and tested for in vitro transfection and in vivo immunogenicity. Blank cationic liposomes of 130.9...
Autores principales: | Peletta, Allegra, Prompetchara, Eakachai, Tharakhet, Kittipan, Kaewpang, Papatsara, Buranapraditkun, Supranee, Techawiwattanaboon, Teerasit, Jbilou, Tayeb, Krangvichian, Pratomporn, Sirivichayakul, Sunee, Manopwisedjaroen, Suwimon, Thitithanyanont, Arunee, Patarakul, Kanitha, Ruxrungtham, Kiat, Ketloy, Chutitorn, Borchard, Gerrit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402479/ https://www.ncbi.nlm.nih.gov/pubmed/34451998 http://dx.doi.org/10.3390/vaccines9080874 |
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