Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1

The application of botulinum neurotoxins (BoNTs) for medical treatments necessitates a potency quantification of these lethal bacterial toxins, resulting in the use of a large number of test animals. Available alternative methods are limited in their relevance, as they are based on rodent cells or n...

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Detalles Bibliográficos
Autores principales: Schenke, Maren, Prause, Hélène-Christine, Bergforth, Wiebke, Przykopanski, Adina, Rummel, Andreas, Klawonn, Frank, Seeger, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402508/
https://www.ncbi.nlm.nih.gov/pubmed/34437455
http://dx.doi.org/10.3390/toxins13080585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402508/
https://www.ncbi.nlm.nih.gov/pubmed/34437455
http://dx.doi.org/10.3390/toxins13080585

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